Polysaccharides from traditional Asian food source and their antitumor activity. Issue 3 (1st October 2021)

• Record Type: Journal Article
• Authors: Yang, Shengfeng; Chen, Xingyu; Sun, Jing; Qu, Chengming; Chen, Xiaolin
• Is Part Of: Journal of food biochemistry. Volume 46:Issue 3(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-10-01
• Subjects: antitumor activity -- polysaccharides -- traditional Asian food source; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; Biochemistry -- Periodicals; 664.024
• DOI: 10.1111/jfbc.13927
• Languages: English
• ISSNs: 0145-8884

Abstract

Abstract: Polysaccharides extracted from Asian traditional food source have been demonstrated to possess different antitumor activities mostly without side effect. In this paper, we reviewed many kinds of polysaccharides from different Asian food source and their antitumor activities. Some are common food such as different mushroom with more research. Some are special e.g., Ginseng, Salvia, Astragalus, Lycium barbarum etc. with relatively fewer research. This review mainly focused on their structure, derivatives, antitumor activities and their mechanism of action in the last decades. It aimed to bridge traditional Asian ingredients with tumor and cancer curation in order to avoid side effect of traditional treatment. Practical applications: There are abundant resources of Asian food. And polysaccharides from these resources have been showed good antitumor activities and immunopotentiating activity. This review introduced the advance of the polysaccharides and their antitumor activities, which will promote the development antitumor medicine derived from Asian food source, or their applications as Adjuvant therapy of traditional chemotherapy and radiotherapy. Due to their multiple antitumor activities, enhancing immunity potential, and non‐toxic side‐effects, it might be utilized for the treatment of multiple tumors and improve the health and the life quality of patients whether as anti‐tumor drugs or as adjuvant therapy method. Furthermore, traditional Asian food source is rich. In the near future, more and more efficient polysaccharides with antitumor activities of Asian food source will be discovered. There will be broad application market for the polysaccharides. Abstract : This paper introduced polysaccharides extracted from Asian traditional food source such as mushrooms, Ginseng, Salvia, Astragalus, Lycium barbarum etc. This review mainly focused on their structure, derivatives, antitumor activities and their mechanism of action in the last decades. The main mechanism of their antitumor was related to their immunopotentiating activity. It aimed to bridge traditional Asian ingredients with tumor and cancer curation in order to avoid side effect of traditional treatment.