A new isoflavone from the fruits of Ficus auriculata and its antibacterial activity. Issue 5 (4th March 2022)

• Record Type: Journal Article
• Authors: Shao, Tai-Ming; Liao, Hai-Xia; Li, Xiao-Bao; Chen, Guang-Ying; Song, Xiao-Ping; Han, Chang-Ri
• Is Part Of: Natural product research. Volume 36:Issue 5(2022)
• Page Start: 1191
• Page End: 1196
• Publication Date: 2022-03-04
• Subjects: Ficus auriculata -- isoflavones -- antibacterial activity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2020.1864368
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: A new isoflavone ( Z )-5, 7, 4′-trihydroxy-3′-[3-hydroxy-3-methyl-1-butenyl] isoflavone (1 ) together with seven known isoflavones (2–8 ) were isolated from the fruits of the Ficus auriculata . Their structures were established on the basis of 1 D, 2 D-NMR spectroscopic data and HR-ESI-MS analysis. All compounds were evaluated for their antibacterial activities against five pathogenic bacteria in vitro . Compounds 3 and 4 exhibited significant antibacterial activities against five pathogenic bacteria with the MIC values ranging from 1.25 to 20 μg/mL.