Population Structure of Macaca fascicularis aurea, and their Genetic Relationships with M. f. fascicularis and M. mulatta Determined by 868 RADseq‐Derived Autosomal SNPs—A consideration for biomedical research. Issue 1 (26th November 2021)

• Record Type: Journal Article
• Authors: Phadphon, Poompat; Kanthaswamy, Sree; Oldt, Robert F.; Hamada, Yuzuru; Malaivijitnond, Suchinda
• Is Part Of: Journal of medical primatology. Volume 51:Issue 1(2022)
• Page Start: 33
• Page End: 44
• Publication Date: 2021-11-26
• Subjects: admixture -- Burmese long‐tailed macaque -- common long‐tailed macaque -- composition -- cynomolgus macaque -- population genetics -- rhesus macaque -- SNPs -- structure; Primates -- Periodicals; Primates -- Diseases -- Periodicals; Medicine, Experimental -- Periodicals; 616.02738
• DOI: 10.1111/jmp.12554
• Languages: English
• ISSNs: 0047-2565

Abstract

Abstract: Background: This study examined the population structure of Macaca fascicularis aurea and their genetic relationships with M . f . fascicularis and M . mulatta . Methods: The study analyzed 868 RADseq‐derived SNPs from samples representing the entire distribution range of M . f . aurea, including their inter‐ and intraspecific hybrid zones. Results: The study supports a M . mulatta /Indochinese M . f . fascicularis, Sundaic M . f . fascicularis, and M . f . aurea trichotomy; M . f . aurea was genetically distinct from both forms of M . f . fascicularis and M . mulatta . Hybridization between M . f . aurea and M . f . fascicularis occurred in two directions: south‐north (8°25′ to 15°56′) and west‐east (98°28′ to 99°02′). Low levels of M . mulatta introgression were also detected in M . f . aurea . Conclusion: This study showcases a complicated scenario of genetic relationships between the M . fascicularis subspecies and between M . fascicularis and M . mulatta and underscores the importance of these taxa's population structure and genetic relationships for biomedical research.