Population Structure of Macaca fascicularis aurea, and their Genetic Relationships with M. f. fascicularis and M. mulatta Determined by 868 RADseq‐Derived Autosomal SNPs—A consideration for biomedical research. Issue 1 (26th November 2021) - Phadphon, Poompat
Abstract: Background: This study examined the population structure of Macaca fascicularis aurea and their genetic relationships with M . f . fascicularis and M . mulatta . Methods: The study analyzed 868 RADseq‐derived SNPs from samples representing the entire distribution range of M . f . aurea, including their inter‐ and intraspecific hybrid zones. Results: The study supports a M . mulatta /Indochinese M . f . fascicularis, Sundaic M . f . fascicularis, and M . f . aurea trichotomy; M . f . aurea was genetically distinct from both forms of M . f . fascicularis and M . mulatta . Hybridization between M . f . aurea and M . f . fascicularis occurred in two directions: south‐north (8°25′ to 15°56′) and west‐east (98°28′ to 99°02′). Low levels of M . mulatta introgression were also detected in M . f . aurea . Conclusion: This study showcases a complicated scenario of genetic relationships between the M . fascicularis subspecies and between M . fascicularis and M . mulatta and underscores the importance of these taxa's population structure and genetic relationships for biomedical research.