Development, optimization, and validation of a method for detection of cartap, thiocyclam, thiosultap-monosodium, and thiosultap-disodium residues in plant foods by GC-ECD. (1st March 2022)

• Record Type: Journal Article
• Authors: Zhang, Jingcheng; Pan, Lixiang; Jing, Jing; Zhuang, Ming; Xin, Jianing; Zhou, Yang; Feng, Xiaoxiao; Zhang, Hongyan
• Is Part Of: Food chemistry. Volume 371(2022)
• Publication Date: 2022-03-01
• Subjects: Nereistoxin (PubChem CID: 15402) -- Cartap (PubChem CID: 27159) -- Thiocyclam (PubChem CID: 35970) -- Thiosultap-monosodium (PubChem CID: 23666830) -- Thiosultap-disodium (PubChem CID: 162117); Nereistoxin -- Cartap -- Thiocyclam -- thiosultap-monosodium -- thiosultap-disodium -- Plant foods; GC-ECD gas chromatography with an electron capture detector -- RSDs relative standard deviations -- NTX Nereistoxin -- LC-MS/MS liquid chromatography coupled to a triple quadrupole mass spectrometer -- rpm revolutions per minute -- MRLs maximum residue limits; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2021.131198
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: A method for detection of four nereistoxin-related pesticides was developed. The established method was applied to 20 plant foods. The pre-processing steps of extraction and derivatization were optimized. Repeatability and reproducibility of the method in 5 laboratories were verified. Abstract: A method was developed for the simultaneous determination of four nereistoxin-related pesticides, viz. cartap, thiocyclam, thiosultap-monosodium, and thiosultap-disodium, in 20 plant foods. The samples were extracted using a hydrochloric acid solution containing cysteine hydrochloride, derivatized to nereistoxin under alkaline conditions, and analyzed by gas chromatography with electron capture detector. The average recoveries of the method were 72–108%, with relative standard deviations (RSDs) of 0.3–14.7% (n = 1200, p < 0.05). The intermediate precision and reproducibility experiments using established methods were also carried out. All the results passed the Cochrane and Grubbs tests (n = 2400, p < 0.05). The RSDs of intermediate precision and RSDs of reproducibility among laboratories were in the ranges 1.7–10.9% and 2.4–15.3% (n = 2400, p < 0.05), respectively, indicating that the accuracy and precision of the method are satisfactory. This method can be used to detect nereistoxin-related pesticides in plant foods.