Digestion and absorption properties of Lycium barbarum polysaccharides stabilized selenium nanoparticles. (30th March 2022)

• Record Type: Journal Article
• Authors: Zhang, Jixian; Yang, Xue; Ji, Tao; Wen, Chaoting; Ye, Zhiqiang; Liu, Xiaofang; Liang, Li; Liu, Guoyan; Xu, Xin
• Is Part Of: Food chemistry. Volume 373:Part B(2022)
• Publication Date: 2022-03-30
• Subjects: Selenium nanoparticles -- Lycium barbarum polysaccharides -- Digestion -- Absorption -- Bioavailability; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2021.131637
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: The digestive properties of SeNPs and LBP-SeNPs was investigated. The absorption of SeNPs and LBP-SeNPs in intestine was clarified. The main absorption site of selenium in intestine is the duodenum. Abstract: In the present study, the digestion and absorption properties of Lycium barbarum polysaccharides stabilized selenium nanoparticles (LBP-SeNPs) were investigated. The results showed that selenium nanoparticles (SeNPs) exhibited a higher selenium release rate than LBP-SeNPs ( p ＜0.05) after being digested in the stages of oral cavity, stomach and intestine. During the digestion process, the particle size of the LBP-SeNPs and SeNPs were both significantly increased, but the particle size of LBP-SeNPs was significantly smaller than that of SeNPs. The results of TEM further indicated that LBP-SeNPs can better maintain the morphology and properties of nanoparticles. Besides, the experiments of the intestinal sac model showed that LBP-SeNPs can better promote the absorption of selenium in various parts (duodenum, jejunum and ileum) of the intestine. Therefore, the LBP can help to improve the structural stability of SeNPs in the digestion process and improve the bioavailability of selenium.