Sensitive surface-enhanced Raman spectroscopy (SERS) determination of nitrofurazone by β-cyclodextrin-protected AuNPs/γ-Al2O3 nanoparticles. (15th February 2022)

• Record Type: Journal Article
• Authors: Bi, Shuyun; Shao, Di; Yuan, Yue; Zhao, Rui; Li, Xu
• Is Part Of: Food chemistry. Volume 370(2022)
• Publication Date: 2022-02-15
• Subjects: Nitrofurazone -- Surface-enhanced Raman spectroscopy (SERS) -- β-CD/AuNPs/γ-Al2O3 nanoparticles -- Duck -- Chicken; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2021.131059
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: The SERS nanosubstrate of β -CD/AuNPs/ γ -Al2 O3 was used to detect nitrofurazone. The enhancement mechanism was discussed in detail. The SERS method for detecting nitrofurazone has superior performance. The SERS methods can realize real-time and on-site detection for veterinary drugs. Abstract: A novel surface-enhanced Raman spectroscopy (SERS) method for the determination of nitrofurazone was developed using AuNPs/ γ -Al2 O3 nanoparticles protected by β -cyclodextrin ( β -CD) as substrate prepared in our lab. The optimum experimental conditions were obtained from single factor procedure and response surface modeling. A linear relationship ( I SERS = 508.96 c + 31987.87, c : nmol L −1, R 2 = 0.996) between SERS intensity and the concentration of nitrofurazone in the range of 3.3 – 667.0 nmol L −1 was established, the limit of detection (LOD) was found at nmol L −1 level (0.37 nmol L −1 by 3 S 0 / S ). The selectivity for the method was studied by the influences of foreign substances on the determination. The recoveries and RSD (n = 5) for the six meat samples were 95.1 % – 104.5% and 2.4 % – 4.8% respectively, which suggesting that the new SERS method was successfully to detecting nitrofurazone.