The functional potential of nine Allium species related to their untargeted phytochemical characterization, antioxidant capacity and enzyme inhibitory ability. (30th January 2022)

• Record Type: Journal Article
• Authors: Rocchetti, Gabriele; Zhang, Leilei; Bocchi, Serena; Giuberti, Gianluca; Ak, Gunes; Elbasan, Fevzi; Yıldıztugay, Evren; Ceylan, Ramazan; Picot-Allain, Marie Carene Nancy; Mahomoodally, Mohamad Fawzi; Lucini, Luigi; Zengin, Gokhan
• Is Part Of: Food chemistry. Volume 368(2022)
• Publication Date: 2022-01-30
• Subjects: Allium -- Organosulfur compounds -- Polyphenols -- Oligosaccharides -- Biological activity; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2021.130782
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Nine understudied Allium species were investigated for their nutraceutical profile. Maceration in methanol provided the highest content of bioactive compounds. The aerial parts showed higher antioxidant activity compared to bulbs. A. cappadocicum bulbs showed the highest inhibition against acetylcholinesterase. The in vitro digestion determined an increase of oligosaccharides. Abstract: In this study, the aerial parts and bulbs of nine Allium species were investigated for their functional phytochemical profile, in vitro antioxidant activities, acetylcholinesterase (AChE), butyrylcholinesterase (BChE), α-amylase, α-glucosidase, and tyrosinase inhibitory properties. Phenolics, alkaloids, glucosinolates and other sulfur-containing compounds were distinctively profiled in the different species. Maceration in methanol allowed recovering the highest cumulative phenolic content in A. scabrifolium (42.31 mg/g), followed by A. goekyigiti (33.15 mg/g) and A. atroviolaceum (28.35 mg/g). The aerial parts of all Allium species showed high in vitro antioxidant activity whereas methanolic extract of A. cappadocicum bulb showed the highest inhibition against AChE (2.44 mg galantamine equivalent/g) and the water extracts of A. isauricum aerial part were the best BChE inhibitors (4.31 mg galantamine equivalent/g). Bulbs were the richer source of oligosaccharides, and in vitro digestion determined an increase of oligosaccharides bioaccessibility. A promising nutraceutical potential could be highlighted in our understudied Allium species.