Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety. (16th September 2021)

• Record Type: Journal Article
• Authors: Yu, Xuetong; Lan, Wenjun; Chen, Meihang; Xu, Su; Luo, Xiaoxi; He, Shuhong; Chen, Haijiang; Fei, Qiang; Wu, Wenneng
• Other Names: Su Yaqiong Academic Editor.
• Is Part Of: Journal of chemistry. Volume 2021(2021)
• Publication Date: 2021-09-16
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1155/2021/8370407
• Languages: English
• ISSNs: 2090-9063

Abstract

Abstract : Seventeen novel N -phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivities against Phomopsis sp., Botryosphaeria dothidea ( B. dothidea ), and Botrytis cinerea ( B. cinerea ) at 50 μ g/mL than pyrimethanil. Unfortunately, the synthesized compounds revealed lower insecticidal activities against Spodoptera frugiperda ( S. frugiperda ) and Mythimna separata ( M. separata ) at 500 μ g/mL than chlorantraniliprole.