Synthesis and Antifungal and Insecticidal Activities of Novel N-Phenylbenzamide Derivatives Bearing a Trifluoromethylpyrimidine Moiety. (16th September 2021) - Yu, Xuetong
Abstract : Seventeen novel N -phenylbenzamide derivatives bearing a trifluoromethylpyrimidine moiety were synthesized via four-step reactions. Their antifungal and insecticidal properties were evaluated. Antifungal test results demonstrated that some of the synthesized compounds showed better in vitro bioactivities against Phomopsis sp., Botryosphaeria dothidea ( B. dothidea ), and Botrytis cinerea ( B. cinerea ) at 50 μ g/mL than pyrimethanil. Unfortunately, the synthesized compounds revealed lower insecticidal activities against Spodoptera frugiperda ( S. frugiperda ) and Mythimna separata ( M. separata ) at 500 μ g/mL than chlorantraniliprole.