Dietary Manganese Exposure in the Adult Population in Germany—What Does it Mean in Relation to Health Risks?. Issue 16 (1st July 2019)

• Record Type: Journal Article
• Authors: Sachse, Benjamin; Kolbaum, Anna Elena; Ziegenhagen, Rainer; Andres, Susanne; Berg, Katharina; Dusemund, Birgit; Hirsch‐Ernst, Karen Ildico; Kappenstein, Oliver; Müller, Frederic; Röhl, Claudia; Lindtner, Oliver; Lampen, Alfonso; Schäfer, Bernd
• Is Part Of: Molecular nutrition & food research. Volume 63:Issue 16(2019)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2019-07-01
• Subjects: food supplements -- manganese -- risk assessment -- TDS‐Exposure -- total diet study; Food -- Biotechnology -- Periodicals; Food -- Microbiology -- Periodicals; Nutrition -- Periodicals; Food -- Toxicology -- Periodicals; Nutrition -- Periodicals; Food Microbiology -- Periodicals; Food Technology -- Periodicals; Molecular Biology -- Periodicals; 664.0705
• DOI: 10.1002/mnfr.201900065
• Languages: English
• ISSNs: 1613-4125

Abstract

Abstract: Manganese is both an essential nutrient and a potential neurotoxicant. Therefore, the question arises whether the dietary manganese intake in the German population is on the low or high side. Results from a pilot total diet study in Germany presented here reveal that the average dietary manganese intake in the general population in Germany aged 14–80 years is about 2.8 mg day −1 for a person of 70 kg body weight. This exposure level is within the intake range of 2–5 mg per person and day as recommended by the societies for nutrition in Germany, Austria, and Switzerland. No information on the dietary exposure of children in Germany can be provided so far. Although reliable information on health effects related to oral manganese exposure is limited, there is no indication from the literature that these dietary intake levels are associated with adverse health effects either by manganese deficiency or excess. However, there is limited evidence that manganese taken up as a highly bioavailable bolus, for example, uptake via drinking water or food supplements, could pose a potential risk to human health—particularly in certain subpopulations—when certain intake amounts, which are currently not well defined, are exceeded. Abstract : Results from a pilot total diet study in Germany presented here reveal that the average dietary manganese intake in the general adult population in Germany is approximately 2.8 mg per person and day. Due to the role of manganese as an essential nutrient and a potential neurotoxicant, information regarding health effects possibly related to oral manganese exposure is critically discussed.