Conjugated Hyperbilirubinemia in Infants: Is There Still a Role for ERCP?. (24th June 2021)

• Record Type: Journal Article
• Authors: Stovicek, Jan; Hlava, Stepan; Keil, Radan; Drabek, Jiri; Lochmannova, Jindra; Koptová, Petra; Wasserbauer, Martin; Frybova, Barbora; Snajdauf, Jiri; Kotalova, Radana; Rygl, Michal
• Other Names: Jarcuska Peter Academic Editor.
• Is Part Of: Canadian journal of gastroenterology & hepatology. Volume 2021(2021)
• Publication Date: 2021-06-24
• Subjects: Digestive organs -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Digestive organs -- Diseases; Gastroenterology; Canada; Digestive System Diseases -- Periodicals; Gastroenterology -- Periodicals; Periodicals; Electronic journals; Fulltext; Internet Resources; Periodicals; 616.3
• DOI: 10.1155/2021/9969825
• Languages: English
• ISSNs: 2291-2789

Abstract

Abstract : Over a twenty-year period, we performed 255 ERCP procedures in infants aged up to 1 year. ERCP was indicated in cholestatic infants with suspicion of biliary obstruction. The most common diagnosis was biliary atresia (48%), choledochal cysts (13%), and choledocholithiasis (4%). The procedure complication rate was 13.7%. Hyperamylasemia occurred in 12.9%. More severe complications were rare‐0.8% of ERCP procedure. There were no cases of postprocedural pancreatitis or death. Our study has proved that ERCP is a safe and reliable method in this age group. Its high specificity and negative predictive value for extrahepatic biliary atresia can prevent unnecessary surgeries in patients with normal bile ducts or endoscopically treatable pathologies.