Evaluating the structural properties of bioactive‐loaded nanocarriers with modern analytical tools. Issue 6 (19th October 2020)

• Record Type: Journal Article
• Authors: Rostamabadi, Hadis; Falsafi, Seid Reza; Assadpour, Elham; Jafari, Seid Mahdi
• Is Part Of: Comprehensive reviews in food science and food safety. Volume 19:Issue 6(2020)
• Page Start: 3266
• Page End: 3322
• Publication Date: 2020-10-19
• Subjects: bioactive compounds -- chemical groups -- crystallinity -- interactions -- nanocarriers -- physical properties -- structural analysis -- thermal properties; Food -- Research -- Periodicals; Food -- Safety measures -- Periodicals; 664.0072
• DOI: 10.1111/1541-4337.12653
• Languages: English
• ISSNs: 1541-4337

Abstract

Abstract: With the emergence of nanocarriers for offering smart transformers improving the bioavailability and functionality of food bioactive compounds, a critical issue is experimental and analytical evaluation of the bioactive‐loaded nanocarriers; so, further technical advancements are necessary for the precise structural characterization of these nanodelivery systems and application of sophisticated analytical techniques. Here, we have portrayed the current progress in the structural characterization approaches including X‐ray diffraction, differential scanning calorimetry, thermogravimetric analysis, fluorescence spectroscopy, circular dichroism, Fourier‐transform infrared spectroscopy, nuclear magnetic resonance, X‐ray photoelectron spectroscopy, and small‐angle X‐ray scattering/small‐angle neutron scattering as powerful and informative tools to have a better control on the design, development, and appraisal of nanoengineered bioactive delivery systems. Different examples and case studies have been tabulated along with illustrative and schematic representation of relevant results. An emerging view concerning the challenges for future structural characterization of these systems is also discussed in detail.