Effect of tartary buckwheat, rutin, and quercetin on lipid metabolism in rats during high dietary fat intake. Issue 1 (27th November 2019)

• Record Type: Journal Article
• Authors: Peng, Lianxin; Zhang, Qu; Zhang, Yanhong; Yao, Zhendong; Song, Panpan; Wei, Lijuan; Zhao, Gang; Yan, Zhuyun
• Is Part Of: Food science & nutrition. Volume 8:Issue 1(2020)
• Page Start: 199
• Page End: 213
• Publication Date: 2019-11-27
• Subjects: gut microbiota -- lipid metabolism -- quercetin -- rutin -- tartary buckwheat; Food industry and trade -- Periodicals; Food -- Periodicals; Nutrition -- Periodicals; 664
• DOI: 10.1002/fsn3.1291
• Languages: English
• ISSNs: 2048-7177

Abstract

Abstract: Tartary buckwheat is rich in flavonoids. However, the health‐promoting effect of these flavonoids has not been adequately studied. In the present study, we investigated the impact of rutin, quercetin, and Tartary buckwheat on the lipid metabolism of rats on a high‐fat diet. Quercetin could significantly reduce body weight, serum triacylglycerol, low‐density lipoprotein cholesterol, TNF‐α, insulin, and ameliorate glucose tolerance. It was surprising that Tartary buckwheat significantly increased the weight of the rats. Rutin, quercetin, and Tartary buckwheat tended to decreased fat deposition in the liver of rats but have little effect on short‐chain fatty acid production. The changes in the structure and diversity of the microbiota were found to be modulated by these diets. It was concluded that quercetin could attenuate high‐fat diet‐induced obesity, rutin, quercetin, and Tartary buckwheat can shape the specific structure of gut microbiota. Mechanism of Tartary buckwheat on lipid metabolism needs further systematic research. Abstract : Tartary buckwheat is rich in flavonoids, and however, the health‐promoting effect of these flavonoids has not been adequately studied. This study reports the impact of rutin, quercetin, and Tartary buckwheat on the lipid metabolism and gut microbiota of rats on a high fat diet.