Anthocyanin-rich extract from purple potatoes decreases postprandial glycemic response and affects inflammation markers in healthy men. (25th April 2020)

• Record Type: Journal Article
• Authors: Jokioja, Johanna; Linderborg, Kaisa M.; Kortesniemi, Maaria; Nuora, Anu; Heinonen, Jari; Sainio, Tuomo; Viitanen, Matti; Kallio, Heikki; Yang, Baoru
• Is Part Of: Food chemistry. Volume 310(2020)
• Publication Date: 2020-04-25
• Subjects: Acylated anthocyanins -- Phenolics -- Purple-fleshed potatoes -- Postprandial state -- Clinical intervention -- Glycemia -- Insulinemia -- Inflammation markers; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2019.125797
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Purple potato extract contained acylated anthocyanins and hydroxycinnamic acids. The potato extract reduced postprandial blood glucose and insulin peaks and iAUC. The hypoglycemic effect was seen in 17 healthy men after a high carbohydrate meal. Acute effects were seen on some of the 90 inflammation markers studied in plasma. Purple potato phenolics increased FGF-19 levels after a high carbohydrate meal. Abstract: Our recent clinical study suggested that polyphenol-rich purple potatoes lowered postprandial glycemia and insulinemia compared to yellow potatoes. Here, 17 healthy male volunteers consumed yellow potatoes with or without purple potato extract (PPE, extracted with water/ethanol/acetic acid) rich in acylated anthocyanins (152 mg) and other phenolics (140 mg) in a randomized cross-over trial. Ethanol-free PPE decreased the incremental area under the curve for glucose ( p = 0.019) and insulin ( p = 0.015) until 120 min after the meal, glucose at 20 min ( p = 0.015) and 40 min ( p = 0.004), and insulin at 20 min ( p = 0.003), 40 min ( p = 0.004) and 60 min ( p = 0.005) after the meal. PPE affected some of the studied 90 inflammation markers after meal; for example insulin-like hormone FGF-19 levels were elevated at 240 min ( p = 0.001). These results indicate that PPE alleviates postprandial glycemia and insulinemia, and affects postprandial inflammation.