Enantioselective Functionalization of Enamides at the β‐Carbon Center with Indoles. (23rd October 2018)
- Record Type:
- Journal Article
- Title:
- Enantioselective Functionalization of Enamides at the β‐Carbon Center with Indoles. (23rd October 2018)
- Main Title:
- Enantioselective Functionalization of Enamides at the β‐Carbon Center with Indoles
- Authors:
- Saputra, Mirza A.
Nepal, Binod
Dange, Nitin S.
Du, Pu
Fronczek, Frank R.
Kumar, Revati
Kartika, Rendy - Abstract:
- Abstract: We report an enantioconvergent approach for the functionalization of enamides at the β‐carbon atom, which involves a chiral Brønsted acid induced tautomerization of 2‐amidoallyl into 1‐amidoallyl cations. These putative reactive intermediates were produced by ionization of racemic α‐hydroxy enamides with a chiral Brønsted acid and captured with substituted indoles in a highly regio‐ and enantioselective manner.
- Is Part Of:
- Angewandte Chemie. Volume 130:Number 47(2018)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 130:Number 47(2018)
- Issue Display:
- Volume 130, Issue 47 (2018)
- Year:
- 2018
- Volume:
- 130
- Issue:
- 47
- Issue Sort Value:
- 2018-0130-0047-0000
- Page Start:
- 15784
- Page End:
- 15788
- Publication Date:
- 2018-10-23
- Subjects:
- 2-Amidoallyl-Kationen -- Asymmetrische Katalyse -- Brønsted-Säuren -- Indole -- Tautomerisierungen
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201808764 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 12290.xml