Methylphenidate and Reduced Overweight in Children With ADHD. Issue 2 (January 2020)

• Record Type: Journal Article
• Authors: Mellström, Elisabeth; Forsman, Cecilia; Engh, Lisbet; Hallerbäck, Maria Unenge; Wikström, Sverre
• Is Part Of: Journal of attention disorders. Volume 24:Issue 2(2020)
• Page Start: 246
• Page End: 254
• Publication Date: 2020-01
• Subjects: children -- pharmacological treatment -- ADHD -- weight; Attention-deficit hyperactivity disorder -- Periodicals; Attention -- Periodicals; 616.8589
• DOI: 10.1177/1087054718808045
• Languages: English
• ISSNs: 1087-0547

Abstract

Objective: The objective of this study was to investigate odds ratios of overweight/obesity in children with ADHD and to compare the change in body mass index (BMI) after initiation of methylphenidate treatment in normal versus overweight/obese children.Method: This population-based study included 724 children (<18 years), of whom 197 were girls. Odds ratios for overweight and obesity were calculated, comparing the study group with a reference group from the same area. After initiation of methylphenidate treatment, changes in BMI were assessed for up to 3 years.Results: Children with ADHD had an odds ratio of 1.87 (95% confidence interval [CI]: [1.60, 2.19]) for overweight/obesity. A decrease in BMI standard deviation score was identified 1 to 3 years into treatment. The decrease was beneficially greater in overweight/obese as compared with normal weight children-mean ( SD ) −0.64 (0.80) versus −0.39 (0.68); p = .001-and greater in girls.Conclusion: Medication with methylphenidate may facilitate favorable weight development in children with ADHD and overweight/obesity.