A mini review of nervonic acid: Source, production, and biological functions. (15th December 2019)

• Record Type: Journal Article
• Authors: Li, Qi; Chen, Jia; Yu, Xiuzhu; Gao, Jin-Ming
• Is Part Of: Food chemistry. Volume 301(2019)
• Publication Date: 2019-12-15
• Subjects: cis-15-Tetracosenoic acid (PubChem CID: 5281120) -- Methyl-cis-15-tetracosenoate (PubChem CID: 5364841); Nervonic acid -- Source -- Production methods -- Brain health; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2019.125286
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Nervonic acid has the identified and potential biological function to brain health. Various sources and production methods of nervonic acid is the crucial basis for its application. For nervonic acid, further research on its mechanism of action is warranted. Abstract: Nervonic acid (NA) has attracted considerable attention because of its close relationship with brain development. Sources of NA include oil crop seeds, oil-producing microalgae, and other microorganisms. Transgenic technology has also been applied to improve the sources and production of NA. NA can be separated and purified by urea adduction fractionation, molecular distillation, and crystallization. Studies on NA functionality involved treatments for demyelinating diseases and acquired immunodeficiency syndrome, as well as prediction of mortality due to cardiovascular diseases and chronic kidney disease. This mini review focuses on the sources, production, and biological functions of NA and provides prospective trends in the investigation of NA.