The matrix of fruit & vegetables modulates the gastrointestinal bioaccessibility of polyphenols and their impact on dietary protein digestibility. (1st February 2018)

• Record Type: Journal Article
• Authors: Dufour, Claire; Loonis, Michèle; Delosière, Mylène; Buffière, Caroline; Hafnaoui, Noureddine; Santé-Lhoutellier, Véronique; Rémond, Didier
• Is Part Of: Food chemistry. Volume 240(2018)
• Page Start: 314
• Page End: 322
• Publication Date: 2018-02-01
• Subjects: Fruit & vegetables -- Gastrointestinal digestion -- Minipig -- Phenolic compounds -- Protein; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2017.07.104
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: First in vivo study (pig) dealing with polyphenol bioaccessibility in the gastric tract. Polyphenol bioaccessibility is low in stomach after F&V or extract ingestion (3.1 or 1.5%). Plant effect: polyphenol diffusion from apple > diffusion from artichoke and plum. Polyphenol bioaccessibility at the ileum in agreement with that for ileostomists. The phenolic extract, but not F&V, decreased the speed and efficiency of protein digestion. Abstract: Fruit and vegetables (F&V) polyphenols have numerous positive health effects, ascribed either to their antioxidant activity within the gastrointestinal tract (GIT) or to bioactivity of their absorbed metabolites. The effect of the F&V matrix on the gastrointestinal bioaccessibility of polyphenols was investigated along with its possible interaction with protein digestion. Minipigs were fed a complete meal with either cubed F&V (apple, plum, artichoke) added, or the corresponding phenolic extract (PE). Gastric and ileal chymes were kinetically collected over the postprandial period. The overall polyphenol bioaccessibility in the stomach was found to be 1.5% and 3.1% after F&V and PE consumption, respectively. The lower release rate from artichoke than from apple showed evidence of a plant effect. Flavanol monomers and glucoside conjugates were not recovered in the ileum in agreement with their absorption in the upper GIT. Interestingly, PE, but not F&V, significantly decreased the speed and efficiency of dietary protein digestion.