[Ir(COD)Cl]2/tris(2, 4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes. Issue 16 (18th April 2018)

• Record Type: Journal Article
• Authors: Liao, Yuan-Xi; Dong, Jie; Hu, Qiao-Sheng
• Is Part Of: Tetrahedron letters. Volume 59:Issue 16(2018)
• Page Start: 1548
• Page End: 1550
• Publication Date: 2018-04-18
• Subjects: Iridium(I) -- Phosphite -- Arylboronic acids -- Aldehydes -- Addition reactions; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2018.02.071
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: First general Ir(I) catalyst for the addition reaction of arylboronic acids with aldehydes. Broad substrate scope. High yields. Abstract: [Ir(COD)Cl]2 /tris(2, 4-di- t -butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes were described. The Ir(I) catalyst, generated from [Ir(COD)Cl]2 and tris(2, 4-di- t -butylphenyl)phosphite, was an efficient catalyst system for the addition reactions of a variety of arylboronic acids with aromatic and aliphatic aldehydes. The easy availability of the catalyst and good yields make these reactions potentially useful in organic synthesis.