[Ir(COD)Cl]2/tris(2, 4-di-t-butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes. Issue 16 (18th April 2018) - Liao, Yuan-Xi
Graphical abstract: Highlights: First general Ir(I) catalyst for the addition reaction of arylboronic acids with aldehydes. Broad substrate scope. High yields. Abstract: [Ir(COD)Cl]2 /tris(2, 4-di- t -butylphenyl)phosphite-catalyzed addition reactions of arylboronic acids with aldehydes were described. The Ir(I) catalyst, generated from [Ir(COD)Cl]2 and tris(2, 4-di- t -butylphenyl)phosphite, was an efficient catalyst system for the addition reactions of a variety of arylboronic acids with aromatic and aliphatic aldehydes. The easy availability of the catalyst and good yields make these reactions potentially useful in organic synthesis.