Activity of Cathelicidin Peptides against Simkania negevensis. (24th February 2011)

• Record Type: Journal Article
• Authors: Donati, Manuela; Di Francesco, Antonietta; Di Paolo, Maria; Fiani, Natascia; Benincasa, Monica; Gennaro, Renato; Nardini, Paola; Foschi, Claudio; Cevenini, Roberto
• Other Names: Bergman Peter Academic Editor.
• Is Part Of: International journal of peptides. Volume 2011(2011)
• Publication Date: 2011-02-24
• Subjects: Peptides -- Periodicals; Peptides; Peptides; Electronic journals; Periodical; Periodicals; Periodicals; Internet Resources; Fulltext
• DOI: 10.1155/2011/708710
• Languages: English
• ISSNs: 1687-9767

Abstract

Abstract : The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μ g/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μ g/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.