Activity of Cathelicidin Peptides against Simkania negevensis. (24th February 2011) - Donati, Manuela
Abstract : The in vitro activity of six cathelicidin peptides against the reference strain Z of Simkania negevensis was investigated. Five peptides—PG-1, Bac7, SMAP-29, BMAP-27, and BMAP-28—proved to be active at very low concentrations (1 to 0.1 μ g/mL), while LL-37 cathelicidin was ineffective even at a concentration of 100 μ g/mL. In comparison to chlamydiae, S. negevensis proved to be more susceptible to the antimicrobial peptides tested.