The use of HPLC-NAA and HPLC-ICP-MS for the speciation of As in infant food. (15th September 2019)

• Record Type: Journal Article
• Authors: Chajduk, Ewelina; Polkowska-Motrenko, Halina
• Is Part Of: Food chemistry. Volume 292(2019)
• Page Start: 129
• Page End: 133
• Publication Date: 2019-09-15
• Subjects: Arsenic -- Infant formulas -- HPLC-ICP-MS -- HPLC-NAA -- Food safety -- Speciation; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2019.04.051
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: HPLC ICP-MS and HPLC NAA have been applied in arsenic speciation analysis. For As, HPLC NAA gives results with better accuracy than HPLC ICP-MS. HPLC NAA could be complementary to HPLC ICP-MS in the speciation analysis. HPLC NAA is valuable analytical tool in QC/QA in the speciation analysis. Abstract: Arsenic and its inorganic species: As (III), As (V), dimethylarsenic acid (DMA) and monomethylarsenic acid (MMA) were determined in hypoallergenic formulas and grain porridges commercially available on Polish market, dedicated for infant 0–8 months. After quantitative extraction with 0.5% HNO3, separation of individual species was performed by high performance liquid chromatography (HPLC), and their determination by neutron activation analysis (NAA) and inductively coupled plasma mass spectrometry (ICP-MS). Due to relatively low content of As in the analysed samples, it was only possible to determine DMA using the HPLC-ICP-MS mode. HPLC separation coupled with off-line determination by NAA enabled the determination of more extracted As species (especially inorganic) with good accuracy. Certified reference material (CRM) Rice Flour SRM 1568b (NIST) was used for the validation of both procedures.