Enantioselective conjugate hydrosilylation of α, β-unsaturated ketones. Issue 21 (12th April 2019)

• Record Type: Journal Article
• Authors: Yang, Huan; Weng, Guanglin; Fang, Dongmei; Peng, Changjiang; Zhang, Yuanyuan; Zhang, Xiaomei; Wang, Zhouyu
• Is Part Of: RSC advances. Volume 9:Issue 21(2019)
• Page Start: 11627
• Page End: 11633
• Publication Date: 2019-04-12
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c9ra01180c
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Enantioselective conjugate hydrosilylation of β, β-disubstituted α, β-unsaturated ketones was realized. Abstract : Enantioselective conjugate hydrosilylation of β, β-disubstituted α, β-unsaturated ketones was realized. In the presence of a chiral picolinamide–sulfonate Lewis base catalyst, the reactions provided various chiral ketones bearing a chiral center at the β-position in up to quantitative yields with moderate enantioselectivities.