Enantioselective conjugate hydrosilylation of α, β-unsaturated ketones. Issue 21 (12th April 2019) - Yang, Huan
Abstract : Enantioselective conjugate hydrosilylation of β, β-disubstituted α, β-unsaturated ketones was realized. Abstract : Enantioselective conjugate hydrosilylation of β, β-disubstituted α, β-unsaturated ketones was realized. In the presence of a chiral picolinamide–sulfonate Lewis base catalyst, the reactions provided various chiral ketones bearing a chiral center at the β-position in up to quantitative yields with moderate enantioselectivities.