Thymus spp. plants - Food applications and phytopharmacy properties. (March 2019)

• Record Type: Journal Article
• Authors: Salehi, Bahare; Abu-Darwish, Mohammad Sanad; Tarawneh, Amer Hussein; Cabral, Celia; Gadetskaya, Anastassiya V.; Salgueiro, Ligia; Hosseinabadi, Tahereh; Rajabi, Sadegh; Chanda, Warren; Sharifi-Rad, Mehdi; Mulaudzi, Rofhiwa Bridget; Ayatollahi, Seyed Abdulmajid; Kobarfard, Farzad; Arserim-Uçar, Dılhun Keriman; Sharifi-Rad, Javad; Ata, Athar; Baghalpour, Navid; Contreras, María del Mar
• Is Part Of: Trends in food science & technology. Volume 85(2019)
• Page Start: 287
• Page End: 306
• Publication Date: 2019-03
• Subjects: Anti-cancer -- Antimicrobial -- Antioxidant -- Clinical studies -- Thyme -- Thymus; AFP Alpha fetoprotein -- AP-1 Activating protein 1 -- BI Browning index -- CK Creatine kinase -- COX Cyclooxygenase -- DPPH 1, 1-Diphenyl- 2-picryl hydrazyl -- EC50 concentration that gives half-maximal response -- EO Essential oil -- GI50 concentration that inhibits the growth of cancer cells by 50% -- GSH Glutathione -- IC50 concentration where the response is reduced by half -- LC50 concentration that causes the death of 50% -- LDH Lactate dehydrogenase -- MAP Modified atmosphere packaging -- MI Mitotic index -- MIC Minimal inhibitory concentration -- MTT (3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide) -- NF-kβ Nuclear factor kappa-light-chain-enhancer of activated B cells -- PBMCs Peripheral blood mononuclear cells -- ROS Reactive oxygen species -- SI Selectivity index -- TBARs Thiobarbituric acid reactive substances; Food industry and trade -- Periodicals; Food -- Biotechnology -- Periodicals; 664.005
• DOI: 10.1016/j.tifs.2019.01.020
• Languages: English
• ISSNs: 0924-2244

Abstract

Abstract: Background: Thymus genus has been used since ancient times for their valuable health properties, which could be attributed to their chemical components, especially essential oils (EOs). Among these species, T. vulgaris has a long history of use for different food and medicinal purposes. Scope and approach: This paper reviews the chemical composition of Thymus plants EOs, including thyme, describes their antimicrobial and antioxidant properties as well as recent food applications as preservatives. The role of these plants in cancer is also covered, as well as the potential these plants have to manage and treat other diseases. Furthermore, clinical studies are also detailed. Key findings and conclusions: Food preservation with naturally occurring compounds is gaining increasing importance due to the consumer demand for safe and high-quality products and to reduce the use of synthetic preservatives. For this purpose, not only thyme but also other thymus plants can be used as such and combined with high-pressure, cold nitrogen plasma, in edible films (active packaging), etc. Moreover, the potential of these plants have to treat several diseases and complications reinforce their use in nutraceuticals and functional foods, but further clinical evidence is required. Highlights: Important applications of Thymus plants in the food industry have been revised. The hurdle concept for food preservation applications seems promising. 3 Thymus plants show significant biological properties and beneficial health effects. Further studies are required to formulate active ingredients based on Thymus plants.