Boronate-crosslinked polysaccharide conjugates for pH-responsive and targeted drug delivery. Issue 8 (11th January 2019)
- Record Type:
- Journal Article
- Title:
- Boronate-crosslinked polysaccharide conjugates for pH-responsive and targeted drug delivery. Issue 8 (11th January 2019)
- Main Title:
- Boronate-crosslinked polysaccharide conjugates for pH-responsive and targeted drug delivery
- Authors:
- Zhang, Yu-Hui
Zhang, Ying-Ming
Yu, Jie
Wang, Jie
Liu, Yu - Abstract:
- Abstract : A polysaccharide nanoconjugate was fabricated from N -(2-aminoethyl)-gluconamide-grafted hyaluronic acid and bortezomib, displaying pH-responsive targeted drug release and higher anticancer effect. Abstract : A pH-responsive and targeted polysaccharide conjugate was fabricated from the boronate linkage of N -(2-aminoethyl)-gluconamide-grafted hyaluronic acid with anticancer drug bortezomib, which could exhibit targeted drug release behaviors at acidic pH and possess lower cytotoxicity and a higher inhibition effect toward cancer cells.
- Is Part Of:
- Chemical communications. Volume 55:Issue 8(2019)
- Journal:
- Chemical communications
- Issue:
- Volume 55:Issue 8(2019)
- Issue Display:
- Volume 55, Issue 8 (2019)
- Year:
- 2019
- Volume:
- 55
- Issue:
- 8
- Issue Sort Value:
- 2019-0055-0008-0000
- Page Start:
- 1164
- Page End:
- 1167
- Publication Date:
- 2019-01-11
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc09956a ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 9430.xml