Molecularly imprinted polymer grafted paper-based method for the detection of 17β-estradiol. (15th April 2017)

• Record Type: Journal Article
• Authors: Xiao, Lei; Zhang, Zhen; Wu, Chuanchen; Han, Liying; Zhang, Hongyan
• Is Part Of: Food chemistry. Volume 221(2017)
• Page Start: 82
• Page End: 86
• Publication Date: 2017-04-15
• Subjects: 17β-Estradiol -- Molecularly imprinted polymer -- Paper-based method; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2016.10.062
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: A MIP grafted paper-based method for the sensitive and specific detection of 17β-E2 was established. Synthetic conditions of MIP were optimized to get good recognition ability. LOD for the detection of milk and human urine samples could reach 0.25 μg L −1 . Abstract: 17β-estradiol (17β-E2 ) usually is used to promote the growth of animal. Abuse of 17β-E2 has become a global food security problem, because the residues in foods can cause endocrine disorder through the food chain. A novel molecularly imprinted polymer (MIP) grafted paper-based method for the sensitive and specific detection of 17β-E2 was reported in this work. Results showed that the MIP's optimum synthetic conditions were as follows: 12 mL of acetonitrile was chosen as the solvent; the molar ratio of template molecule, functional monomer and cross linker was 1:12:12. MIP synthesized had a good recognition ability, the limit of detection (LOD) of established detection method for milk and human urine samples could reach 0.25 μg L −1 .