Biosynthesis of novel daidzein derivatives using Bacillus amyloliquefaciens whole cells. Issue 6 (2nd November 2018)

• Record Type: Journal Article
• Authors: Kim, Kyu-Min; Park, Jin-Soo; Choi, HaeRi; Kim, Min-Seon; Seo, Joo-Hyun; Pandey, Ramesh Prasad; Kim, Jin Woo; Hyun, Chang-Gu; Kim, Seung-Young
• Is Part Of: Biocatalysis and biotransformation. Volume 36:Issue 6(2018)
• Page Start: 469
• Page End: 475
• Publication Date: 2018-11-02
• Subjects: Biotransformation -- Resting cells -- Daidzein -- Novel compound -- Bacillus amyloliquefaciens; Enzymes -- Biotechnology -- Periodicals; Enzymes -- Industrial applications -- Periodicals; Biotransformation (Metabolism) -- Periodicals; 660.63
• DOI: 10.1080/10242422.2018.1461212
• Languages: English
• ISSNs: 1024-2422

Abstract

Abstract: Biotransformation of daidzein was performed by using Bacillus amyloliquefaciens KCTC 13588, Lactococcus lactis subsp. lactis KCTC 3769, Leuconostoc citreum KCTC 13186, Kluyveromyces lactis var. lactis KCTC 17704, Pediococcus pentosaceus KCTC 3116, and Lactobacillus sakei KCTC 13416 cells as a biocatalyst. Four derivatives of daidzein such as daidzein-7- O -phosphate, daidzein-7- O - β -D-glucoside, daidzein-7- O - β- (6′′- O -succinyl)-D-glucoside, and 4′ - Ethoxy-daidzein-7- O-β- (6′′- O -succinyl)-D-glucoside were isolated from the biotransformation reaction mixture. The structures of the molecules were elucidated by HPLC, HR-QTOF-ESI/MS and 1 H-NMR analyses. Among them 4′ - Ethoxy-daidzein-7- O-β- (6′′- O -succinyl)-D-glucoside derivative is novel compound and not reported elsewhere till now.