Analysis and engineering of substrate shuttling by the acyl carrier protein (ACP) in fatty acid synthases (FASs). Issue 82 (28th September 2018)
- Record Type:
- Journal Article
- Title:
- Analysis and engineering of substrate shuttling by the acyl carrier protein (ACP) in fatty acid synthases (FASs). Issue 82 (28th September 2018)
- Main Title:
- Analysis and engineering of substrate shuttling by the acyl carrier protein (ACP) in fatty acid synthases (FASs)
- Authors:
- Rossini, Emanuele
Gajewski, Jan
Klaus, Maja
Hummer, Gerhard
Grininger, Martin - Abstract:
- Abstract : Perturbations of domain–domain interactions impact the function of type I fatty acid synthases. Abstract : Perturbations of domain–domain interactions impact the function of type I fatty acid synthases. We identify interface point mutations that modulate fatty acid chain lengths, and explain their effect in changes of domain–domain binding energetics. Engineering of similar interfaces in related megasynthases may be exploited for custom synthesis of natural products.
- Is Part Of:
- Chemical communications. Volume 54:Issue 82(2018)
- Journal:
- Chemical communications
- Issue:
- Volume 54:Issue 82(2018)
- Issue Display:
- Volume 54, Issue 82 (2018)
- Year:
- 2018
- Volume:
- 54
- Issue:
- 82
- Issue Sort Value:
- 2018-0054-0082-0000
- Page Start:
- 11606
- Page End:
- 11609
- Publication Date:
- 2018-09-28
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c8cc06838k ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7984.xml