Dietary exposure to trace elements and health risk assessment in the region of Valencia, Spain: a total diet study. Issue 2 (1st February 2017)

• Record Type: Journal Article
• Authors: Marín, Silvia; Pardo, Olga; Báguena, Rosario; Font, Guillermina; Yusà, Vicent
• Is Part Of: Food additives & contaminants. Volume 34:Issue 2(2017)
• Page Start: 228
• Page End: 240
• Publication Date: 2017-02-01
• Subjects: Exposure assessment -- total diet studies -- metal analysis -- metal speciation -- risk assessment; Food additives -- Periodicals; Food contamination -- Periodicals; 664.06
• DOI: 10.1080/19440049.2016.1268273
• Languages: English
• ISSNs: 1944-0049

Abstract

ABSTRACT: Dietary exposure of the Valencian region population to lead, cadmium, inorganic arsenic (iAs), chromium, copper, tin and methylmercury (meHg) was assessed in a total diet study carried out in the region of Valencia in 2010–11. A total of 8100 food samples were collected and analysed. Occurrence data were combined with consumption data to estimate dietary exposure in adults (> 15 years of age) and young children (6–15 years of age). The estimated intake was calculated by a probabilistic approach. Average intake levels (optimistic scenario) for lead, iAs, chromium and tin were 0.21, 0.08, 1.79 and 1.87 µg kg − 1 bw day −1 respectively; for Cd and meHg average intake levels were 0.77 and 0.54 µg kg – 1 bw week −1, respectively, and for Cu, 1.60 mg day −1 . In terms of risk characterisation, the results showed that 2.84% of the adult population may exceed the BMDL10 (benchmark dose lower confidence limit) established for Pb, which is linked to renal effects; whereas 28.01% of the young children population may exceed the BMDL01 related to neurodevelopment effects. In addition, 8.47% of the adult population and 12.32% of young children exceeded the meHg tolerable weekly intake (TWI). GRAPHICAL ABSTRACT: