Wood, M. R., Noetzel, M. J., Engers, J. L., Bollinger, K. A., Melancon, B. J., Tarr, J. C., Han, C., West, M., Gregro, A. R., Lamsal, A., Chang, S., Ajmera, S., Smith, E., Chase, P., Hodder, P. S., Bubser, M., Jones, C. K., Hopkins, C. R., Emmitte, K. A., Niswender, C. M., Wood, M. W., Duggan, M. E., Conn, P. J., Bridges, T. M., & Lindsley, C. W. (2016). discovery and optimization of a novel series of highly CNS penetrant M4 PAMs based on a 5, 6-dimethyl-4-(piperidin-1-yl)thieno[2, 3-d]pyrimidine core. Bioorganic & medicinal chemistry letters, 26(13), 3029–3033. http://access.bl.uk/ark:/81055/vdc_100032636412.0x000044