Radical arylation of tyrosine residues in peptides. Issue 48 (1st December 2016)
- Record Type:
- Journal Article
- Title:
- Radical arylation of tyrosine residues in peptides. Issue 48 (1st December 2016)
- Main Title:
- Radical arylation of tyrosine residues in peptides
- Authors:
- Fehler, Stefanie K.
Pratsch, Gerald
Östreicher, Christiane
Fürst, Michael C.D.
Pischetsrieder, Monika
Heinrich, Markus R. - Abstract:
- Abstract: The radical arylation of the phenolic side chain of tyrosine in peptides was investigated. Aryl radicals were generated from aryldiazonium salts using titanium(III) chloride as stoichiometric reductant. Due to the high selectivity with which 3-aryltyrosine derivatives were formed, this reaction type represents a new strategy for the direct functionalization of peptides. Graphical abstract:
- Is Part Of:
- Tetrahedron. Volume 72:Issue 48(2016)
- Journal:
- Tetrahedron
- Issue:
- Volume 72:Issue 48(2016)
- Issue Display:
- Volume 72, Issue 48 (2016)
- Year:
- 2016
- Volume:
- 72
- Issue:
- 48
- Issue Sort Value:
- 2016-0072-0048-0000
- Page Start:
- 7888
- Page End:
- 7893
- Publication Date:
- 2016-12-01
- Subjects:
- Radical reaction -- Arylation -- Diazonium -- Tyrosine -- Peptide
Chemistry, Organic -- Periodicals
547.005 - Journal URLs:
- http://www.elsevier.com/journals ↗
- DOI:
- 10.1016/j.tet.2016.04.084 ↗
- Languages:
- English
- ISSNs:
- 0040-4020
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 8796.850000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 7511.xml