Analysis of isophthalaldehyde in migration samples from polyethylene terephthalate packaging. Issue 8 (3rd August 2018)

• Record Type: Journal Article
• Authors: Osorio, Jazmín; Úbeda, Sara; Aznar, Margarita; Nerín, Cristina
• Is Part Of: Food additives & contaminants. Volume 35:Issue 8(2018)
• Page Start: 1645
• Page End: 1652
• Publication Date: 2018-08-03
• Subjects: Isophthalaldehyde -- hollow-fibre liquid-phase microextraction -- solid-phase microextraction -- poly(ethylene terephthalate) -- migration; Food additives -- Periodicals; Food contamination -- Periodicals; 664.06
• DOI: 10.1080/19440049.2018.1465208
• Languages: English
• ISSNs: 1944-0049

Abstract

ABSTRACT: In the present work, different pre-concentration strategies were evaluated for the analysis of isophthalaldehyde in migration samples from food packaging materials. This compound is a potential migrant in several copolymers used for food packaging, and since it is considered a non-intentionally added substance, its concentration in migration samples must be determined. Derivatisation was the first sample treatment evaluated. o-(2, 3, 4, 5, 6-Pentafluorobenzyl)hydroxylamine was tested as derivatisation agent, but no satisfactory results were obtained. Then, hollow-fibre liquid-phase microextraction (HF-LPME) and solid-phase microextraction were optimised. The HF-LPME method showed the highest sensitivity, achieving an enrichment factor of 60-fold. The limit of detection of the method was 10 ng g −1, the limit of quantification was 30 ng g −1 and the relative standard deviation was 6.1%. Finally, the method was applied to migration studies to evaluate the safety in use of a poly(ethylene terephthalate) packaging material. The content of isophthalaldehyde was determined in two aqueous food simulants: 10% ethanol (v/v) and 3% acetic acid (w/v). Different migration conditions were tested. The results obtained showed a considerable rise in the concentration of isophthalaldehyde when increasing the time and temperature of the migration experiment. Graphical Abstract: