Imidazolium ionic liquids-based salting-out extraction of 2, 3-butanediol from fermentation broths. (August 2018)

• Record Type: Journal Article
• Authors: Dai, Jianying; Wang, Hui; Li, Yan; Xiu, Zhi-Long
• Is Part Of: Process biochemistry. Volume 71(2018)
• Page Start: 175
• Page End: 181
• Publication Date: 2018-08
• Subjects: Salting-out extraction -- 2, 3-butanediol -- Ionic liquids -- Partition behavior -- Fermentation broth; Biochemical engineering -- Periodicals; Biotechnology -- Periodicals; Biochemistry -- periodicals; Biotechnology -- periodicals; Chemical Engineering -- periodicals; Génie biochimique -- Périodiques; Biotechnologie -- Périodiques; Biochemical engineering; Biotechnology; Periodicals; 660.63
• DOI: 10.1016/j.procbio.2018.05.015
• Languages: English
• ISSNs: 1359-5113

Abstract

Graphical abstract: Highlights: Partition of 2, 3-butandiol in ionic liquid-based aqueous two-phase systems. [C2 mim][CF3 SO3 ]- and [C4 mim][Cl]-K2 HPO4 systems were studied. Different trends of partition coefficient variation were observed. Selectivity for glucose, succinic acid and lactic acid was investigated. 95.7% 2, 3-Butanediol and 99.5% [C2 mim][CF3 SO3 ] were distributed to the top phase. Abstract: Salting-out extraction is an efficient technique for the separation of bio-based chemicals from fermentation broths. So far, salting-out extraction of 2, 3-butanediol has mainly focused on systems composed of organic solvents and salts, while less attention has been given to the green solvent ― ionic liquids. In this research, imidazolium ionic liquids were used to examine the recovery of 2, 3-butanediol from fermentation broths. The influences of the temperature and concentration of 2, 3-butanediol on phase formation were determined using two systems of 1-butyl-3-methylimidazolium chloride ([C4 mim][Cl])-K2 HPO4 and 1-ethyl-3-methylimidazolium trifluoromethanesulfonate ([C2 mim][CF3 SO3 ])-K2 HPO4 . The partition behaviors of 2, 3-butandiol and ionic liquids, and the selectivity of 2, 3-butanediol over glucose and organic acids were investigated and compared at different concentrations of ionic liquids and K2 HPO4 . Most of 2, 3-butanediol and ionic liquids were distributed to the top phase, whereas different trends of partition coefficient variation were observed. Under the condition of 25% [C2 mim][CF3 SO3 ]-30% K2 HPO4 ( w/w ), the recovery of 2, 3-butanediol and [C2 mim][CF3 SO3 ] was 95.7% and 99.5%, respectively, and selectivity for glucose, succinic acid and lactic acid was 2.59, 115 and 20.8, respectively.