Bioactivities of phytochemicals in Araiostegia yunnanensis (Christ). (1st November 2015)

• Record Type: Journal Article
• Authors: Chen, Longsheng; Xu, Wei; Shao, Rong; Du, Xianfeng
• Is Part Of: Food chemistry. Volume 186(2015)
• Page Start: 37
• Page End: 45
• Publication Date: 2015-11-01
• Subjects: DPPH 2, 2-diphenyl-1-picrylhydrazyl -- ABTS 2, 2′-azinobis-(3-ethylbenzoth-iazoline-6-sulphonic acid -- NBT nitrotetrazolium blue chloride -- PMS phenazine methosulphate -- NADH nicotinamide adenine dinucleotide; Flavonoids -- Antioxidant -- Anticancer -- HPLC–DAD–ESI-MS -- Araiostegia yunnanensis; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2014.07.113
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: The phytochemicals of Araiostegia yunnanensis ( Christ ) Cop were investigated. The total flavonoid content had been determined. The antioxidant and anticancer bioactivity had been evaluated. The evaluation of the acetylcholinesterase inhibition had also been studied. Abstract: The profile and bioactivity of phytochemicals in Araiostegia yunnanensis ( Christ ) Cop were investigated. The total flavonoids content in A. yunnanensis is about 84.90 mg/g. By means of HPLC–DAD–ESI-MS, the main flavonoids in A. yunnanensis were tentatively identified as myricetin 3- O -rhamnosylglucoside, eriodictyol 7- O -rutinoside, quercetin 3- O -rutinoside, luteolin-7- O -apiosylglucoside, quercetin 3- O -rhamnosylgalactoside, and luteolin 7- O -glucoside. The extract (0.268 mg/ml total flavonoids) from A. yunnanensis showed very strong superoxide anion radical scavenging potential and reducing power, which are higher than those of rutin (0.25 mg/ml). The extract (0.268 mg/ml total flavonoids) from A. yunnanensis exhibited similar DPPH scavenging activity with rutin (0.25 mg/ml). However, rutin (0.25 mg/ml) showed a significantly higher ABTS radical scavenging effect than that of the extract (0.268 mg/ml total flavonoids) from A. yunnanensis. The methanol extract from A. yunnanensis showed obviously cytotoxic effects on A549 cells and it had no effect against acetylcholinesterase.