Zipper-like magnetic molecularly imprinted microspheres for on/off-switchable recognition and extraction of 17β-estradiol from food samples. (30th September 2018)

• Record Type: Journal Article
• Authors: Zhu, Wenting; Peng, Hailong; Luo, Mei; Yu, Ningxiang; Xiong, Hua; Wang, Ronghui; Li, Yanbin
• Is Part Of: Food chemistry. Volume 261(2018)
• Page Start: 87
• Page End: 95
• Publication Date: 2018-09-30
• Subjects: Zipper-like -- On/off-switchable recognition -- Molecularly imprinted microspheres -- 17β-Estradiol; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2018.04.034
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Positive thermo-responsive and magnetic SM-MIMs were developed. Zipper-like on/off switchable binding or releasing for template molecule. High binding capacity, eco-friendly elution, and efficient separation. Using as dispersive SPE sorbent for 17β-E2 pretreatment of food samples. Abstract: Zipper-like on/off-switchable and magnetic molecularly imprinted microspheres (SM-MIMs) were constructed using acrylamide (AAm) and 2-acrylamide-2-methyl propanesulfonic acid (AMPS) as functional monomers for 17β-estradiol (17β-E2 ) recognition and extraction. The imprinted polymer interactions between poly(AAm) (PAAm) and poly(AMPS) (PAMPS) with on/off-switchable property to temperature, exhibited dissociation at relatively higher temperatures (such as 30 °C) and helped 17β-E2 enter into imprinted sites, leading to higher binding capability. Conversely, the interpolymer complexes between PAAm and PAMPS formed and blocked 17β-E2 access to imprinted sites at lower temperature (such as 20 °C). SM-MIMs were used as dispersive solid phase extraction (SPE) adsorbent with HPLC for 17β-E2 pretreatment and detection in food samples, and low limit detection (2.52 µg L −1 ) and quantification (10.76 µg L −1 ) with higher recovery were obtained. Therefore, SM-MIMs may be a promising adsorbent for 17β-E2 pretreatment in food samples owing to its advantages of on/off-switchable recognition, eco-friendly elution, and efficient separation.