Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism. Issue 7 (12th December 2017)

• Record Type: Journal Article
• Authors: Sun, Jiaheng; Xin, Qi; Yang, Yang; Shah, Hameed; Cao, Hongqian; Qi, Yanfei; Gong, Jian Ru; Li, Junbai
• Is Part Of: Chemical communications. Volume 54:Issue 7(2018)
• Page Start: 715
• Page End: 718
• Publication Date: 2017-12-12
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc08820e
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Photosensitizers can be excited by nitrogen-doped graphene quantum dots under one-/two-photon excitation through an intramolecular FRET mechanism and induced phototoxicity. Abstract : A novel material with a large two-photon absorption cross-section was conjugated with a typical photosensitizer for inducing a FRET process. The photosensitizer can be excited by a one-/two-photon laser and then induced photo-toxicity in vitro and in vivo . The system presents great potential for improving treatment depth and the precision of traditional photodynamic therapy.