Nitrogen-doped graphene quantum dots coupled with photosensitizers for one-/two-photon activated photodynamic therapy based on a FRET mechanism. Issue 7 (12th December 2017) - Sun, Jiaheng
Abstract : Photosensitizers can be excited by nitrogen-doped graphene quantum dots under one-/two-photon excitation through an intramolecular FRET mechanism and induced phototoxicity. Abstract : A novel material with a large two-photon absorption cross-section was conjugated with a typical photosensitizer for inducing a FRET process. The photosensitizer can be excited by a one-/two-photon laser and then induced photo-toxicity in vitro and in vivo . The system presents great potential for improving treatment depth and the precision of traditional photodynamic therapy.