Vasorelaxant activity of twenty-one physiologically relevant (poly)phenolic metabolites on isolated mouse arteries. Issue 12 (15th November 2017)

• Record Type: Journal Article
• Authors: Van Rymenant, E.; Grootaert, C.; Beerens, K.; Needs, P. W.; Kroon, P. A.; Kerimi, A.; Williamson, G.; García-Villalba, R.; González-Sarrías, A.; Tomas-Barberan, F.; Van Camp, J.; Van de Voorde, J.
• Is Part Of: Food & function. Volume 8:Issue 12(2017)
• Page Start: 4331
• Page End: 4335
• Publication Date: 2017-11-15
• Subjects: Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; Nutrition -- Periodicals; 664.07
• DOI: 10.1039/c7fo01273j
• Languages: English
• ISSNs: 2042-6496

Abstract

Abstract : Polyphenols are beneficial for health, but are metabolised after consumption. Abstract : Polyphenols are beneficial for health, but are metabolised after consumption. We compared the vasorelaxant capacity of twenty-one physiologically relevant polyphenol metabolites in isolated mouse arteries. Hesperetin, urolithins and ferulic acid-4- O -sulfate – not their glucuronidated forms or ferulic acid – caused vasorelaxation. Therefore, we advise the use of relevant conjugates in future mechanistic research.