Enantioselective Rhodium‐Catalyzed Coupling of Arylboronic Acids, 1, 3‐Enynes, and Imines by Alkenyl‐to‐Allyl 1, 4‐Rhodium(I) Migration. Issue 51 (24th November 2017)

• Record Type: Journal Article
• Authors: Callingham, Michael; Partridge, Benjamin M.; Lewis, William; Lam, Hon Wai
• Is Part Of: Angewandte Chemie international edition. Volume 56:Issue 51(2017)
• Page Start: 16352
• Page End: 16356
• Publication Date: 2017-11-24
• Subjects: allylation -- asymmetric catalysis -- imines -- isomerization -- rhodium; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201709334
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: A chiral rhodium complex catalyzes the highly enantioselective coupling of arylboronic acids, 1, 3‐enynes, and imines to give homoallylic sulfamates. The key step is the generation of allylrhodium(I) species by alkenyl‐to‐allyl 1, 4‐rhodium(I) migration. Abstract : A chiral rhodium complex catalyzes the highly enantioselective coupling of arylboronic acids, 1, 3‐enynes, and imines to give homoallylic sulfamates. The key step is the generation of allylrhodium(I) species by alkenyl‐to‐allyl 1, 4‐rhodium(I) migration. t Am= tert ‐amyl.