Poly(propylene)-based Films Modified with a Tetracationic Phthalocyanine with Applications in Photodynamic Inactivation of Candida albicans. Issue 3 (11th February 2018)

• Record Type: Journal Article
• Authors: Tempesti, Tomas; Alvarez, M. Gabriela; Gómez, César; Strumia, Miriam; Durantini, Edgardo N.
• Is Part Of: Polymer-plastics technology and engineering. Volume 57:Issue 3(2018)
• Page Start: 166
• Page End: 174
• Publication Date: 2018-02-11
• Subjects: Antimicrobial -- photoactive surface -- photodynamic inactivation -- phthalocyanine -- polymeric films; Polymers -- Periodicals; Polymerization -- Periodicals; Polymers -- Periodicals; Engineering -- Periodicals; Plastics -- Periodicals; 668.9
• DOI: 10.1080/03602559.2017.1315643
• Languages: English
• ISSNs: 0360-2559

Abstract

ABSTRACT: Photoactive films based on polymer-like poly(propylene) were generated and utilized as support of zinc(II)tetramethyltetrapyridino[2, 3- b :2′, 3′- g :2″, 3″- l :2″′, 3″′- q ]porphyrazinium salt (ZnTM2, 3PyPz). Using a photograft polymerization of acrylic acid, the poly(propylene) film was functionalized with carboxyl groups (PP- g -PAAc), which attached ZnTM2, 3PyPz by electrostatic bond to form PP- g -PAAc-Pc films. In vitro investigations indicated that PP- g -PAAc-Pc films produced photodynamic inactivation of Candida albicans cells, mainly mediated by a contribution of type II process. According to the results, the photodynamic activity produced by the PP- g -PAAc-Pc film and visible light irradiation can successfully inactivate C. albicans deposited on the surface of the films. GRAPHICAL ABSTRACT: