A rapid and simple HPLC–FLD screening method with QuEChERS as the sample treatment for the simultaneous monitoring of nine bisphenols in milk. (1st April 2018)

• Record Type: Journal Article
• Authors: Xiong, Lin; Yan, Ping; Chu, Min; Gao, Ya-Qin; Li, Wei-Hong; Yang, Xiao-Ling
• Is Part Of: Food chemistry. Volume 244(2018)
• Page Start: 371
• Page End: 377
• Publication Date: 2018-04-01
• Subjects: Bisphenol A (PubChem CID: 6623) -- Bisphenol B (PubChem CID: 66166) -- Bisphenol C (PubChem CID: 6620) -- Bisphenol E (PubChem CID: 608116) -- Bisphenol F Diglycidyl Ether (PubChem CID: 91511) -- Bisphenol F bis (2, 3-dihydroxyprophy) Ether (PubChem CID: 3928015) -- Bisphenol F Glycidyl 2, 3-Dihydroxypropyl Ether (PubChem CID: 71360307) -- Bisphenol A Bis (2, 3-dihydroxyprophy) Ether (PubChem CID: 110678) -- Bisphenol A diglycidyl ether (PubChem CID: 2286); Bisphenols -- QuEChERS -- HPLC–FLD -- Milk; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2017.10.030
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: A new rapid analytical method for BPs in milk is developed. Combination QuEChERS–HPLC is applied. QuEChERS is firstly applied to determination of BPs. The method is rapider, cheaper, excellent recovery and RSDs, very low LOD and LOQ. The sample preparation is environmentally friendly. Abstract: A specific, precise and accurate high performance liquid chromatographic (HPLC) analytical method with a fluorescence detector (FLD) was established for the simultaneous determination of nine bisphenols (BPs) in milk samples. Samples were extracted ultrasonically with acetonitrile and cleaned using the QuEChERS technique. Under the optimized conditions, good linearity was obtained for the nine BPs and the correlation coefficients (R 2 ) ranged from 0.9942 to 0.9997. Recovery values for the nine bisphenols in spiked samples were 75.82–93.86% with intra-day and inter-day relative standard deviations (RSDs) from 2.6 to 11.1%. The limits of detection (LODs) and quantification (LOQs) were 1.0–3.1 μg/kg and 3.5–9.8 μg/kg, respectively. The results demonstrated clearly that the approach developed provides reliable, simple, rapid and environmentally-friendly quantification and identification of nine bisphenols in a fatty matrix and could be used for monitoring bisphenols in milk.