Stabilization of alpha-lipoic acid by complex formation with octenylsuccinylated high amylose starch. (1st March 2018)

• Record Type: Journal Article
• Authors: Li, Yi-Xuan; Park, Eun Young; Lim, Seung-Taik
• Is Part Of: Food chemistry. Volume 242(2018)
• Page Start: 389
• Page End: 394
• Publication Date: 2018-03-01
• Subjects: Alpha-lipoic acid -- In vitro digestibility -- Octenylsuccinylated high amylose starch -- Stability; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2017.09.028
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Thermal and oxidation stability of ALA in starch dispersions was compared. Octenylsuccinylated high amylose starch (OS) was most effective in protecting ALA. Amylose complex formation contributed to stabilization and slow release of ALA. Amphiphilic nature of OS was responsible for the stabilizing ALA. Abstract: The thermal and oxidative stability of alpha-lipoic acid (ALA) in aqueous dispersions containing beta-cyclodextrin (CD), native high amylose (HA) and octenylsuccinylated high amylose (OS) starches (0.1% ALA and 1.0% CD or starch solids) were compared. Both native and modified starches increased the stability of ALA against thermal degradation and oxidation at higher degrees than CD. The OS was more effective in stabilizing ALA than HA. The ALA loss in the dispersions occurred mainly in the supernatant, suggesting that the complex formation of ALA with amylose played a key role in the stabilization. In an in vitro digestion test, the release of ALA from OS dispersion was less than that of HA dispersion, indicating that ALA complexed with OS amylose was most stable against digestion. The octenylsuccinylated high amylose starch was an effective protecting agent for ALA in aqueous media, as well as a delivery carrier for ALA in digestive tract.