Assessing renal function in patients receiving DOACs: Cockcroft-Gault versus estimated glomerular filtration rate. Issue 157 (September 2017)

• Record Type: Journal Article
• Authors: Kruger, Paul C.; Robinson, Marlene A.; Xu, Ke; Siegal, Deborah M.; Eikelboom, John W.; Bhagirath, Vinai C.
• Is Part Of: Thrombosis research. Issue 157(2017)
• Page Start: 165
• Page End: 166
• Publication Date: 2017-09
• Subjects: Cockcroft-Gault -- Glomerular filtration rate -- Renal -- Direct oral anticoagulant; Thrombosis -- Periodicals; 616.135
• DOI: 10.1016/j.thromres.2017.07.020
• Languages: English
• ISSNs: 0049-3848

Abstract

Highlights: Randomised trials and guidelines for direct oral anticoagulants (DOACs) assess renal function by creatinine clearance. We compare the results of creatinine clearance obtained by the Cockcroft-Gault formula with results of eGFR obtained by MDRD and CKD-EPI formulae for patients receiving DOACs. Differences in results of these three formulae can substantially impact DOAC dosing.