Assessing renal function in patients receiving DOACs: Cockcroft-Gault versus estimated glomerular filtration rate. Issue 157 (September 2017) - Kruger, Paul C.
Highlights: Randomised trials and guidelines for direct oral anticoagulants (DOACs) assess renal function by creatinine clearance. We compare the results of creatinine clearance obtained by the Cockcroft-Gault formula with results of eGFR obtained by MDRD and CKD-EPI formulae for patients receiving DOACs. Differences in results of these three formulae can substantially impact DOAC dosing.