Increased torulene accumulation in red yeast Sporidiobolus pararoseus NGR as stress response to high salt conditions. (15th December 2017)

• Record Type: Journal Article
• Authors: Li, Chunji; Zhang, Ning; Li, Bingxue; Xu, Qiong; Song, Jia; Wei, Na; Wang, Wenjing; Zou, Hongtao
• Is Part Of: Food chemistry. Volume 237(2017)
• Page Start: 1041
• Page End: 1047
• Publication Date: 2017-12-15
• Subjects: Carotenoids -- Torulene -- Health-promoting effects -- NaCl -- Commercial production; Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; 664
• DOI: 10.1016/j.foodchem.2017.06.033
• Languages: English
• ISSNs: 0308-8146

Abstract

Highlights: Torulene, a carotenoid, possesses potential health-promoting effects in human. Sporidiobolus pararoseus NGR, accumulates torulene, β-carotene and torularhodin. Treatment with NaCl showed a remarkable increase in torulene production. Abstract: Carotenoids represent a class of molecules valuable for food, chemical and pharmaceutical industries. As a microbial carotenoid, torulene possesses potential health-promoting effects in human. However, few studies have been conducted to investigate optimal condition for its large-scale commercial production to date. Sporidiobolus pararoseus NGR, a pigmented yeast, was shown previously to accumulate considerable amounts of torulene, β-carotene, and torularhodin. In this study, the effect of salt stress on the production of carotenoids in S. pararoseus NGR was investigated. After 5 days of cultivation, the total amount of carotenoids was significantly higher in 0.75 M (3.952 mg/L) and 1 M (2.89 mg/L) NaCl treatments than control (1.636 mg/L), respectively. Among them, the increase in torulene accumulation is the main contributor to the improvement in total amount of carotenoids under 0.75 and 1 M NaCl treatments. Together, our results should advance the development of metabolic engineering for the commercial production of torulene.