Non-edible parts of Solanum stramoniifolium Jacq. – a new potent source of bioactive extracts rich in phenolic compounds for functional foods. Issue 5 (10th May 2017)

• Record Type: Journal Article
• Authors: Svobodova, Blanka; Barros, Lillian; Sopik, Tomas; Calhelha, Ricardo C.; Heleno, Sandrina; Alves, Maria Jose; Walcott, Simone; Kuban, Vlastimil; Ferreira, Isabel C. F. R.
• Is Part Of: Food & function. Volume 8:Issue 5(2017)
• Page Start: 2013
• Page End: 2021
• Publication Date: 2017-05-10
• Subjects: Food -- Analysis -- Periodicals; Food -- Composition -- Periodicals; Nutrition -- Periodicals; 664.07
• DOI: 10.1039/c7fo00297a
• Languages: English
• ISSNs: 2042-6496

Abstract

Abstract : Caffeoylquinic acid derivatives, flavonoids and polyamines were the main compounds identified. The root extract gave the highest antioxidant potential and also significantly inhibited the growth of MCF-7 and HepG2 tumor cell lines. Abstract : Extracts prepared from leaves, roots, and stems of Solanum stramoniifolium Jacq. (Solanaceae) in 80% ethanol have been tested for their in vitro antioxidant, anti-inflammatory, antimicrobial, and cytotoxic activities with an aim to find new sources of substances for functional foods and food additives. The root extract revealed the highest antioxidant activity in all assays exceeding the trolox capacity, and was the only extract that inhibited nitric oxide production in mouse macrophage cells, showing also the capacity to suppress the growth of all tested human tumor cell lines (MCF-7, NCI-H460, HeLa and HepG2). The leaf extract showed the strongest antimicrobial activity inhibiting all tested clinical isolates. To the author's best knowledge it was the first time that all individual parts of this plant were tested for biological activity together with the phenolic compound characterization.