An efficient and eco-friendly synthesis of 2-pyridones and functionalized azaxanthone frameworks via indium triflate catalyzed domino reaction. Issue 11 (28th April 2017)

• Record Type: Journal Article
• Authors: Poomathi, N.; Perumal, P. T.; Ramakrishna, S.
• Is Part Of: Green chemistry. Volume 19:Issue 11(2017)
• Page Start: 2524
• Page End: 2529
• Publication Date: 2017-04-28
• Subjects: Environmental chemistry -- Industrial applications -- Periodicals; Environmental management -- Periodicals; 660
• DOI: 10.1039/c6gc03440c
• Languages: English
• ISSNs: 1463-9262

Abstract

Abstract : A green and efficient one-pot method has been developed for the synthesis of 2-pyridone and functionalized azaxanthone frameworks using indium triflate as an environmentally friendly, reusable catalyst. Abstract : A green and efficient one-pot method has been developed for the synthesis of 2-pyridone and functionalized azaxanthone frameworks using indium triflate as an environmentally friendly, reusable catalyst. In this one-pot reaction, 3-formylchromones display a diverse pattern of reactivity upon reaction with different classes of alkenes. An indium triflate-promoted reaction with ( Z )- N -methyl-1-(methylthio)-2-nitroethenamine leads to 3-formylchromone annulations to 2-pyridone and analogues via a remarkably facile chromone ring opening. The analogous reaction with N, N' -dimethyl-2-nitro-ethene-1, 1-diamine results in the formation of synthetically useful functionalized azaxanthones via a 6π-electrocyclization reaction.